Our Facility

Located 15 min from Toronto Pearson International Airport, the core capabilities of Covar’s formulation development and clinical supply manufacture facilities are:

  •  High potency clinical supply manufacture

  • Wide variety of dosage form capabilities

  • Miniaturization equipment for API sparing

Covar also provides full on-site analytical support, including method development, validation, and ICH stability testing.

  • Tablet Manufacture

    • Single & bi-layer compression (Piccola Bilayer, instrumented)

    • Tablet & pellet coating (O’Hara)

    • Blending (≤ 2 cu ft)

    • Milling (comil/hammer mill)

    • Granulation (wet & dry)

    Encapsulation

    • Liquid & powder filling

    • Capsule banding

    • Blister packing (thermoform, cold form)

    Liquids, semi-solids & suspensions manufacture

    Particle size reduction

    • Micronization (micron size)

    • Microfluidizer (nanoparticles)

    Packaging & labelling

    • Blister packing (thermoform, cold form)

    • Vacuum sealing

    • Bottle & induction sealing

    • Clinical supply labelling (open label & double blinded)

    • DSC

    • Dissolution & disintegration

    • FTIR & UV-Vis

    • HPLC (DAD, VWD, RID)

    • LC/MS (triple quadrupole)

    • Flash purification (Biotage)

    • Moisture analysis (LOD, KF)

    • Optical microscopy

    • Particle size (sieve analysis, laser diffraction)

    • PXRD

    • pH

    • Powder flow analysis & physical testing for tablets

    • TOC

    • Viscosity

    • ICH stability & photostability studies

Outside view of high-potency processing suite.

Outside view of high-potency processing suite.

Analytical laboratories at Covar Pharmaceuticals

Analytical laboratories at Covar Pharmaceuticals